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| Catalog: | C0446A |
| Product Type: | Antibody |
| Reactivity: | H |
| Analysis mode: | WB,IHC,ELISA |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 0.5 mg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification method: | Antigen affinity purification |
| Application: | Cancer, Immunology, Tags and Cell Markers |
| Conjugation: | Unconjugated |
| Immunogen: | MAGEA3 |
| Swiss port: | P43357 |
| Gene accession: | NP005353 |
| Celluar localization: | Endoplasmic reticulum,endoplasmic reticulum |
| Tissue specificity: | It is expressed in many types of tumors, such as melanoma, head and neck squamous cell carcinoma, lung cancer and breast cancer, but not expressed in normal tissues, except for the testis and placenta. |
This gene belongs to the MAGEA gene family. The proteins encoded by members of this family have a sequence recognition rate of 50% to 80%. The promoter of MAGEA gene and the first exon showed considerable differences, indicating that the existence of this gene family allows the same function to be expressed under different transcriptional control. The MAGEA gene is clustered on chromosome Xq28. They are involved in some genetic diseases, such as congenital dyskeratosis.
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