| Catalog: | C0305A |
| Product Type: | Antibody |
| Reactivity: | H,M,R |
| Analysis mode: | WB,IHC,ELISA |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1.02 mg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification method: | Antigen affinity purification |
| Application: | Cell Biology, Epigenetics and Nuclear Signaling |
| Conjugation: | Unconjugated |
| Immunogen: | L3MBTL2 |
| Swiss port: | Q969R5 |
| Gene accession: | BC017191 |
| Celluar localization: | Nucleus |
L3MBTL2 is the abbreviation for Lethal(3) malignant brain tumor-like 2 protein. The PcG protein maintains the transcriptional inhibition state of genes, possibly through the modification of chromatin, which changes its genetic expression. Its association with a pigment remodeling complex suggests that it may help prevent the expression of genes that trigger cells to enter mitosis. Combines with monomethylated and dimethylated'Lys-20' on histone H4. In combination with histone H3 peptides, these histone H3 peptides are monomethylated or dimethylated on'Lys-4','Lys-9' or'Lys-27'.
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