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| Catalog: | C0029A |
| Product Type: | Antibody |
| Reactivity: | H |
| Analysis mode: | IHC |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.05% Proclin300 and 50% glycerol, pH7.3 |
| Purification method: | Antigen affinity purification |
| Application: | Cancer, Neuroscience, Tags & Cell Markers, Signal Transduction, Cell Biology |
| Conjugation: | Unconjugated |
| Immunogen: | KLK6 |
| Swiss port: | Q92876 |
| Genn_ID: | 5653 |
| Celluar localization: | Cytoplasm, Endoplasmic reticulum, Mitochondrion, Nucleus, Secreted |
| Tissue specificity: | Highest concentrations found in glandular tissues such as salivary glands followed by lung, colon, fallopian tube, placenta, breast, pituitary and kidney. Overexpressed in primary breast tumors but not expressed in metastatic tumors. |
More and more evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.
Diagnostic Development
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