JAM-A/Junctional Adhesion Molecule A ELISA Kit

This JAM-A/Junctional Adhesion Molecule A ELISA Kit, Human is an enzyme-linked immunosorbent assay for the quantitative measurement of Human JAM-A/Junctional Adhesion Molecule A protein in Serum,Cell supernatant,Lysate . It contains recombinant Human JAM-A/Junctional Adhesion Molecule A, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer.