Catalog: | C0159T |
Product Type: | Test kit |
Size: | 96 wells |
Priciple: | Sandwich ELISA |
Assay time: | 3.5 h |
Detection range: | 1.25-80 pg/mL |
Sample type: | Serum, Urine, Cerebrospinal fluid, Bronchoalveolar lavage, Amniotic fluid, Plasma, COVID-19 |
Analysis mode: | ELISA |
Storage: | 2-8℃ |
Application: | Cytokines and chemokines and related molecules, Energy metabolism and body weight regulation, Sepsis, COVID-19 |
IL-6 is a cytokine that has pleiotropic effects on inflammation, immune response, hematopoiesis and tumorigenesis. IL-6 is expressed in a variety of cells, such as adipocytes, fibroblasts, osteoblasts, endothelial cells, neurons, lymphocytes, monocytes, neutrophils, etc., and its expression depends on cell activation. The circulating IL-6 levels in healthy people are very low, about 1 pg/mL, but during inflammation, IL-6 levels rise rapidly. The anti-inflammatory properties of IL-6 are mainly responsible for antibacterial and beneficial regeneration processes. The pro-inflammatory properties of IL-6 have a negative impact on chronic inflammation and autoimmunity. Increased levels of IL-6 have been found in patients with atherosclerotic cardiovascular disease, insulin resistance, type 2 diabetes, atopic asthma, rheumatoid arthritis, advanced cancer, and micrometastasis in blood circulation.
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