IL24 polyclonal antibody

This gene is a member of the IL10 cytokine family. It has been identified as a gene induced during terminal differentiation of melanoma cells. The protein encoded by this gene can selectively induce apoptosis in a variety of cancer cells. Overexpression of this gene leads to increased expression of multiple genes in the GADD family, and is related to the induction of apoptosis. In melanoma cells, phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38) and heat shock 27kDa protein 1 (HSPB2/HSP27) was found, but this gene was not found in normal immortal melanoma cells. Induce. In addition, it has also been reported that splice transcript variants encode different subtypes. IL24 (Interleukin 24) is a protein-coding gene. Diseases associated with IL24 include melanoma and subclavian theft. The related pathways include PEDF-induced signaling pathway and immune response IL-23 signaling pathway. The GO annotations associated with this gene include cytokine activity.