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Human PCSK9/Proprotein Convertase 9 ELISA Kit

  • Product Information
  • Description
Catalog: C-EL-2065T
Product Type: Test kit
Size: 96 tests
Principle: Sandwich ELISA
Species: Human
Detection range: 0.156-10 ng/mL
Sensitivity: 0.01 ng/mL
Sample type: Serum, Plasma, Cell culture supernatants, Cell lysates
Test type: Quantitative
Analysis mode: ELISA
Storage: All the reagents are stored at 2-8℃. Refer to the protocol for further storage instructions.
Synonyms:: FH3, HCHOLA3, LDLCQ1, NARC 1, NARC1, PC9, PCSK9, Proprotein convertase 9
Application: OX40 (CD134) is a member of the TNFR-superfamily of receptors. Predominantly expressed on activated T cells, OX40 is activated by its cognate ligand OX40L (CD134L) and functions as a T cell co-stimulatory molecule. OX40-OX40L interactions have been proposed as a potential therapeutic target for treating autoimmunity. OX40 can interact with TRAF2, TRAF3, and TRAF5. In addition to a membrane bound form, OX40 also exists as a soluble form, released by activated lymphocytes.

This test kit is a solid phase sandwich Enzyme Linked-Immuno-Sorbent Assay (Sandwich ELISA). The PCSK9 ELISA kit is to be used to detect and quantify protein levels of endogenous PCSK9. The assay recognizes human PCSK9. An antibody specific for PCSK9 has been pre-coated onto the microwells. The PCSK9 protein in samples is captured by the coated antibody after incubation. Following extensive washing, another antibody of biotinylated specific for PCSK9 is added to detect the captured PCSK9 protein. For signal development, Streptavidin-HRP is added, followed by Tetramethyl-benzidine (TMB) reagent. Solution containing sulfuric acid is used to stop color development and the color intensity which is proportional to the quantity of bound protein is measurable at 450nm with the correction wavelength set at 630 nm.

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