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| Catalog: | C-EL-2043T |
| Product Type: | Test kit |
| Size: | 96 tests |
| Principle: | Sandwich ELISA |
| Species: | Human |
| Detection range: | 31.25-2000 pg/mL |
| Sensitivity: | 1.1 pg/mL |
| Sample type: | Serum, Plasma, Cell culture supernatants, Urine |
| Test type: | Quantitative |
| Analysis mode: | ELISA |
| Storage: | All the reagents are stored at 2-8℃. Refer to the protocol for further storage instructions. |
| Synonyms:: | HAVCR, HAVCR 1, HAVCR1, Kidney injury molecule 1, KIM 1, KIM1, T cell membrane protein 1, TIM, TIM 1, TIM1, TIMD 1, TIMD1 |
| Application: | Interleukin 8 (IL8), also known as CXCL8, which is a member of the CXC chemokine family. This chemokine is secreted by a variety of cell types including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, and various tumor cell lines in response to inflammatory stimuli. IL8 has two primary functions. It induces chemotaxis in target cells, primarily neutrophils but also other granulocytes, causing them to migrate toward the site of infection. IL8 also induces phagocytosis once they have arrived. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. IL8 is also known to be a potent promoter of angiogenesis. IL8 has been associated with tumor angiogenesis, metastasis, and poor prognosis in breast cancer. IL-8 may present a novel therapeutic target for estrogen driven breast carcinogenesis and tumor progression. |
This test kit is a solid phase sandwich Enzyme Linked-Immuno-Sorbent Assay (Sandwich ELISA). The KIM-1 ELISA kit is to be used to detect and quantify protein levels of endogenous KIM-1. The assay recognizes human KIM-1. An antibody specific for KIM-1 has been pre-coated onto the microwells. The KIM-1 protein in samples is captured by the coated antibody after incubation. Following extensive washing, another antibody specific for KIM-1 is added to detect the captured KIM-1 protein. For signal development, Streptavidin-HRP is added, followed by Tetramethyl-benzidine (TMB) reagent. Solution containing sulfuric acid is used to stop color development and the color intensity which is proportional to the quantity of bound protein is measurable at 450nm with the correction wavelength set at 630 nm.
Core Diagnostic Capabilities
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