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| Catalog: | C-EL-1992T |
| Product Type: | Test kit |
| Size: | 96 tests |
| Principle: | Sandwich ELISA |
| Species: | Human |
| Detection range: | 0.625-40 ng/mL |
| Sensitivity: | 0.16 ng/mL |
| Sample type: | Serum, Plasma |
| Test type: | Quantitative |
| Analysis mode: | ELISA |
| Storage: | All the reagents are stored at 2-8℃. Refer to the protocol for further storage instructions. |
| Synonyms:: | CBP 35, CBP35, GAL3, GALBP, Galectin 3, L 31, Lectin L 29, LGALS2, LGALS3 |
| Application: | FKBPL, also named as DIR1, NG7 and WISp39, has similarity to the immunophilin protein family, which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is thought to have a potential role in the induced radioresistance, probably by increasing the rate of DNA repair in cells exposed to X rays. Breast cancer cells stably overexpressing FKBPL became dependent on estrogen for their growth and were dramaticaly more sensitive to the antiestrogens Tamoxifen and Fulvestrant, whereas FKBPL knockdown reverses this phenotype. FKBPL is an estrogen-inducible gene that acts as a cochaperone in ERa/Hsp90 molecular complexes; furthermore, FKBPL levels may be both a prognostic indicator and determinant of response to endocrine therapy. This kit is used to quantify FKBPL level in vivo. |
This test kit is a solid phase sandwich Enzyme Linked-Immuno-Sorbent Assay (Sandwich ELISA). The human Galectin-3 ELISA kit is to be used to detect and quantify protein levels of endogenous human . The assay recognizes human Galectin-3. An antibody specific for human Galectin-3 has been pre-coated onto the microwells. The human Galectin-3 protein in samples is captured by the coated antibody after incubation. Following extensive washing, another antibody of biotinylated specific for human Galectin-3 is added to detect the captured human Galectin-3 protein. For signal development, Streptavidin-HRP is added, followed by Tetramethyl-benzidine (TMB) reagent. Solution containing sulfuric acid is used to stop color development and the color intensity which is proportional to the quantity of bound protein is measurable at 450nm with the correction wavelength set at 630 nm.
Core Diagnostic Capabilities
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