USA: 
Europe: 
Email: 
Consultation
| Catalog: | C-EL-1978T |
| Product Type: | Test kit |
| Size: | 96 tests |
| Principle: | Sandwich ELISA |
| Species: | Human |
| Detection range: | 78.1-5000 pg/mL |
| Sensitivity: | 0.1 pg/mL |
| Sample type: | Serum, Plasma, Cell culture supernatants |
| Test type: | Quantitative |
| Analysis mode: | ELISA |
| Storage: | All the reagents are stored at 2-8℃. Refer to the protocol for further storage instructions. |
| Synonyms:: | ECM1, extracellular matrix protein 1, Secretory component p85 |
| Application: | CXCL9, also named MIG, is a member of the CXC family and has an important role in the chemotaxis of immune cells. CXCL9 is secreted by various cell types including immune cells (T lymphocytes, NK cells, dendritic cells, macrophages, eosinophils etc.), and non-immune cells (hepatic stellate cells, preadipocytes, thyrocytes, endothelial cell, tumor cells, and fibroblasts etc). CXCL9 plays role to induce chemotaxis, promote differentiation and multiplication of leukocytes, and cause tissue extravasation. Functions of CXCL9 are mostly mediated through its receptor CXCR3, which initiates intracellular signaling pathways like p38 and Erk. CXCL9 is involved in the pathogenesis of a variety of physiologic diseases during their initiation and their maintenance. |
This test kit is a solid phase sandwich Enzyme Linked-Immuno-Sorbent Assay (Sandwich ELISA). The ECM1 ELISA kit is to be used to detect and quantify protein levels of endogenous ECM1. The assay recognizes human ECM1. An antibody specific for ECM1 has been pre-coated onto the microwells. The ECM1 protein in samples is captured by the coated antibody after incubation. Following extensive washing, another horseradish peroxidase (HRP)-conjugated antibody specific for ECM1 is added to detect the captured ECM1 protein. For signal development, followed by Tetramethyl-benzidine (TMB) reagent. Solution containing sulfuric acid is used to stop color development and the color intensity which is proportional to the quantity of bound protein is measurable at 450nm with the correction wavelength set at 630 nm .
Core Diagnostic Capabilities
Follow Us -
Copyright © 2024 Creative Biogene. All rights reserved.
