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| Catalog: | C1318T |
| Product Type: | Test kit |
| Unit: | 96 tests |
| Assay time: | 2.5 hours |
| Limit of detection: | 0.065 amol/μl |
| Sample type: | Tissue extract, Whole blood, Cultural lysates (HEK, HeLa) |
| Sample requirements: | 10 µl/well |
| Analysis mode: | miREIA – miRNA enzyme immunoassay |
| Application: | Oncology, Reproduction, Neurodegenerative disease |
It was found that miR-100 in cerebrospinal fluid (CSF) from Alzheimer’s disease (AD) patients could serve as one of the reliable biomarkers to detect AD. MiR-99b-5p/100-5p has been found to promote cell apoptosis with the Amyloid β (Aβ) treatment. Dynamic change of miR-99b-5p/100-5p levels during Aβ-associated pathologies might be attributed to Aβ-induced endoplasmic reticulum stress (ER stress).
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