Catalog: | C0114A |
Product Type: | Antibody |
Analysis mode: | WB, IHC, ELISA |
Species specificity: | Human, mouse, rat |
Host: | Rabbit |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 350 μg/mL |
Storage: | -20℃ |
Buffer: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 |
Purification method: | Antigen affinity purification |
Conjugation: | Unconjugated |
Immunogen: | HEXB |
Genn_ID: | 3074 |
Gene accession: | BC017378 |
The HEXB gene encodes a subunit of the hexosaminidase enzyme, which is involved in the breakdown of gangliosides. It is responsible for the degradation of GM2 gangliosides, and there are many other molecules containing terminal n-acetylhexosamine in the brain and other tissues. With reference to HEXB and glycosylation domains, mw63-67kda precursors will have some different bands; 59-63 kDa signal peptide is removed, 50-55kda subunit (or signal and propeptide removal), 20-25 kDa subunit B chain , Chain A subunit ~ 30kda.
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