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| Catalog: | C0281A |
| Product Type: | Antibody |
| Reactivity: | H,M |
| Analysis mode: | IHC |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 2 mg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.02% sodium azide and 50% glycerol pH 7.4 |
| Purification method: | Affinity purification |
| Application: | Cancer, Cardiovascular, Metabolism, Signal transduction |
| Conjugation: | Unconjugated |
| Immunogen: | Hepcidin |
| Swiss port: | P81172 |
| Celluar localization: | Secreted |
| Tissue specificity: | The liver expresses the highest amount, while the heart and brain express lower amounts. The lungs, tonsils, salivary glands, trachea, prostate, adrenal glands, and thyroid have low levels. |
This gene can be used as a signal molecule to participate in the maintenance of iron homeostasis. It is necessary to regulate intestinal iron absorption and macrophage iron storage together with HFE. It has strong antibacterial activity against Escherichia coli ML35P N. cinerea, and has weak antibacterial activity against Staphylococcus epidermidis, Staphylococcus aureus and group b Streptococcus. It is active against white c. albicans. It has no activity against Pseudomonas aeruginosa.
Diagnostic Development
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