GSTM1 polyclonal antibody

This gene encodes glutathione S-transferase, which belongs to the mu class. mu enzymes, by binding to glutathione, play a role in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and oxidative stress products. These genes are highly polymorphic. These genetic variations can alter an individual's susceptibility to carcinogens and toxins, as well as the toxicity and efficacy of certain drugs. Null mutations in this mu gene have been associated with an increase in many cancers, possibly due to increased sensitivity to environmental toxins and carcinogens.