USA:

Europe:

Email:

Consultation

FITC Anti-Mouse FcεRIα Antibody

  • Product Information
  • Description
Catalog: C-FC-1306A
Product Type: FCM Antibody
Size: 50 tests/100 tests/200 tests
Reactivity: Mouse
Analysis mode: FCM
Host: Armenian Hamster
Isotype: Armenian Hamster IgG
Alternate names: High affinity immunoglobulin epsilon receptor subunit alpha,Fc-epsilon RI-alpha,FcERI,Fcer1a
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: FITC
Buffer: PBS with 0.05% Proclin300, 1% BSA
Swiss port: P20489
Clone NO.: MAR-1
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.

Verification Code
top