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| Catalog: | C-FC-4753A |
| Product Type: | FCM Antibody |
| Size: | 0.5 mg/ml |
| Reactivity: | Mouse |
| Positive FC: | mouse splenocytes |
| Recommended dilution: | This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
| Analysis mode: | FC |
| Host: | Armenian Hamster |
| Isotype: | IgG |
| Alternate names: | 5830438K24Rik, AI452015, AIM, Cd69, CD69 antigen, VEA |
| Storage: | 2-8°C |
| Purification method: | Affinity purification |
| Immunogen: | Mouse dendritic epidermal T cell line Y245 |
| Genn_ID: | 12515 |
| Gene accession: | BC106997 |
| Gene symbol: | Cd69 |
| Buffer: | Phosphate based buffer with 0.09% sodium azide and 0.1% gelatin, pH 7.2. |
CD69, also known as AIM, EA-1, Leu-23, and MLR3, is a type II transmembrane glycoprotein that belongs to the C-type lectin superfamily (PMID: 8340758; 7804122). CD69 is constitutively expressed by mature thymocytes, platelets, several subsets of tissue resident immune cells (including resident memory T cells and gamma delta T cells), and is inducibly expressed by activated T cells, B cells, natural killer (NK) cells, monocytes, neutrophils (PMID: 8100776; 28475283). CD69 has been identified as an early activation marker of lymphocytes and is commonly used as a marker of activated lymphocytes and NK cells (PMID: 28475283; 25759842). It is involved in the regulation of immune responses (PMID: 15745855).
Core Diagnostic Capabilities
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