USA: 
Europe: 
Email: 
Consultation
| Catalog: | C-FC-4712A |
| Product Type: | FCM Antibody |
| Size: | 20 µl/test |
| Reactivity: | Human |
| Positive FC: | mouse splenocytes |
| Recommended dilution: | This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
| Analysis mode: | FC |
| Host: | Mouse |
| Isotype: | Mouse IgG1 |
| Alternate names: | CD62L, gp90 MEL, hLHRc, L selectin, LAM 1, LAM1, LECAM1, Leu 8, Leukocyte adhesion molecule 1, LNHR, LSEL, Lyam 1, LYAM1, Lymph node homing receptor, PLNHR, selectin L, SELL, TQ1 |
| Storage: | 2-8°C |
| Purification method: | The purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography. |
| Immunogen: | PMA-activated human peripheral blood leukocytes |
| Genn_ID: | 20343 |
| Gene accession: | BC052681 |
| Gene symbol: | Sell |
| Buffer: | PBS with 0.1% sodium azide. |
CD62L, also known as L-selectin or SELL, is a member of the selectin family of adhesion molecules that also include CD62E (E-selectin) and CD62P (P-selectin) (PMID: 2663882, 2473156, 1382078). CD62L is a highly glycosylated protein of 95-105 kDa on neutrophils and 74 kDa on lymphocytes (PMID: 1382078; 1694883, 1695155). CD62L is expressed on the surface of most leukocytes, including lymphocytes, neutrophils, monocytes, eosinophils, hematopoietic progenitor cells, and immature thymocytes (PMID: 1694883, 1688580). It mediates the binding of lymphocytes to high endothelial venules (HEV) of peripheral lymph nodes through interactions with a constitutively expressed ligand, and is also involved in lymphocyte, neutrophil, and monocyte attachment to endothelium at sites of inflammation (PMID: 1382078).
Core Diagnostic Capabilities
Follow Us -
Copyright © 2025 Creative Biogene. All rights reserved.
