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FITC Anti-Human CD54 Antibody

  • Product Information
  • Description
Catalog: C-FC-1169A
Product Type: FCM Antibody
Size: 20 tests/50 tests/100 tests/200 tests
Reactivity: Human
Analysis mode: FCM
Host: Mouse
Isotype: Mouse IgG1, κ
Alternate names: Intercellular adhesion molecule 1,Icam1,MALA-2,MyD10,CD54,Icam-1
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: FITC
Buffer: PBS with 0.05% Proclin300, 1% BSA
Swiss port: P05362
Clone NO.: 15.2
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 µl staining volume or per 100 µl of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelial cells, high endothelial venules, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. The expression of ICAM-1 can be released from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyte extravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds to CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95) as well as hyaluronan and fibrinogen.

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