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| Catalog: | C-FC-4688A |
| Product Type: | FCM Antibody |
| Size: | 40 μg/ml |
| Reactivity: | Human |
| Positive FC: | Human peripheral blood lymphocytes |
| Recommended dilution: | This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl(0.125µg) per 10^6 cells in a 100 µl suspension or 5 µl(0.125µg) per 100 µl of whole blood. |
| Analysis mode: | FC |
| Host: | Mouse |
| Isotype: | IgG2b |
| Alternate names: | B lymphocyte antigen CD20, B1, Bp35, CD20, LEU 16, MS4A1, MS4A1,CD20, MS4A2, S7 |
| Storage: | 2-8°C |
| Purification method: | Affinity purification |
| Immunogen: | Human tonsillar B cells |
| Genn_ID: | 931 |
| Gene accession: | BC002807 |
| Gene symbol: | MS4A1 |
| Buffer: | Phosphate based buffer with 0.09% sodium azide and 0.1% gelatin, pH 7.2. |
CD20 is a 33-37 kDa transmembrane phosphoprotein belonging to the membrane-spanning 4A family (PMID: 3260267; 16785532). CD20 is a B-lymphocyte surface molecule that is widely expressed during B-cell ontogeny, from early pre-B-cell developmental stages until final differentiation into plasma cells (PMID: 7524522). CD20 functions as calcium-permeable cation channel (PMID: 7684739). It is involved in the regulation of B-cell activation, proliferation and differentiation (PMID: 7524522).
Core Diagnostic Capabilities
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