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| Catalog: | C-FC-4684A |
| Product Type: | FCM Antibody |
| Size: | 10 µl/test |
| Reactivity: | Human |
| Positive FC: | human peripheral blood monocytes |
| Recommended dilution: | This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 10 µl per 10^6 cells in a 100 µl suspension or 10 µl per 100 µl of whole blood. |
| Analysis mode: | FC |
| Host: | Mouse |
| Isotype: | IgG2a |
| Alternate names: | CD14, CD14 molecule |
| Storage: | 2-8°C |
| Purification method: | Affinity purification |
| Immunogen: | Thymocytes and peripheral blood lymphocytes from a remission AML patient |
| Genn_ID: | 929 |
| Gene accession: | BC010507 |
| Gene symbol: | CD14 |
| Buffer: | PBS with 0.1% sodium azide. |
CD14 is a 50-55 kDa glycosylphosphatidylinositol-anchored glycoprotein preferentially expressed on monocytes and macrophages, and at lower levels on granulocytes (PMID: 3385210; 2462937; 7685797). CD14 can also exist as a soluble protein. CD14 acts as a co-receptor for bacterial liposaccharides (LPS) (PMID: 1698311). It plays a major role in the inflammatory response of monocytes to LPS.
Core Diagnostic Capabilities
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