Catalog: | C0232A |
Product Type: | Antibody |
Reactivity: | M |
Analysis mode: | IHC |
Host: | Rabbit |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 0.7 mg/mL |
Storage: | -20℃ |
Buffer: | PBS with 0.05% Proclin300,and 50% glycerol, pH7.3 |
Purification method: | Affinity purification |
Application: | Cancer, Cardiovascular, Signal Transduction, Neuroscience, Stem Cells, Developmental Biology |
Conjugation: | Unconjugated |
Immunogen: | FGF2 |
Swiss port: | P15655 |
Genn_ID: | 14173 |
Celluar localization: | Nucleus, Secreted |
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and have extensive mitotic and angiogenic activities. This protein is involved in a variety of biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA of this gene contains multiple polyadenylation sites, which can be translated alternately from non-AUG (CUG) and AUG start codons, resulting in 5 different isomers. The subtype initiated by cug is located in the nucleus and is responsible for intranuclear effects, while the subtype initiated by augo is mainly cytoplasmic and is responsible for the paracrine and autocrine effects of FGF.
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