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| Catalog: | C0438A |
| Product Type: | Antibody |
| Reactivity: | H,M,R |
| Analysis mode: | WB,IHC-p,ELISA |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Purification method: | Antigen affinity purification |
| Application: | Cancer, Cell Biology, Signal Transduction |
| Conjugation: | Unconjugated |
| Immunogen: | Seprase |
| Swiss port: | Q12884 |
| Gene accession: | BC026250 |
| Celluar localization: | Cell membrane |
| Tissue specificity: | Fibroblast specific |
The protein encoded by this gene is a homodimer integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive mesenchymal fibroblasts of epithelial carcinoma, granulation tissue of healing wounds, bone malignant cells, melanoma and soft tissue sarcoma. This protein is believed to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.
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