Catalog: | C0761A |
Product Type: | Antibody |
Reactivity: | H |
Analysis mode: | IHC,ELISA |
Host: | Rabbit |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1.5 mg/mL |
Storage: | -20℃ |
Buffer: | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification method: | Antigen affinity purification |
Application: | Epigenetics and Nuclear Signaling |
Conjugation: | Unconjugated |
Immunogen: | FANCE |
Swiss port: | Q9HB96 |
Gene accession: | NP068741 |
Celluar localization: | Nucleus |
Fanconi Anemia Complement Group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2) ). Fanconi anemia is a genetically heterogeneous recessive genetic disease characterized by genetic instability of cells, hypersensitivity to DNA cross-linking agents, increased chromosome damage, and defects in DNA repair. The sequences of the members of the Fanconi anemia complementation group do not have similarities. They are connected to each other by assembling into a common nuclear protein complex. This gene encodes the protein of the E complementation group.
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