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FAAP24 polyclonal antibody

  • Product Information
  • Description
Catalog: C0758A
Product Type: Antibody
Reactivity: H,M
Analysis mode: IHC,ELISA
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 0.84 mg/mL
Storage: -20℃
Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification method: Antigen affinity purification
Application: Epigenetics and Nuclear Signaling
Conjugation: Unconjugated
Immunogen: FAAP24
Swiss port: Q9BTP7
Gene accession: NP689479
Celluar localization: Nucleus

FAAP24 (Fanconi anemia-associated protein of 24 kDa) plays a role in DNA repair by recruiting FA core complex to damage DNA. Regulate the effect of FANCD2 single base effect on DNA damage. When inhibited, it can cause chromosomal instability and hypersensitivity to DNA cross-linking agents. The FANCM/FAAP24 complex binds to DNA and preferentially binds to single-stranded DNA.

Verification Code

Diagnostic Development

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