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| Catalog: | C0758A |
| Product Type: | Antibody |
| Reactivity: | H,M |
| Analysis mode: | IHC,ELISA |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 0.84 mg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification method: | Antigen affinity purification |
| Application: | Epigenetics and Nuclear Signaling |
| Conjugation: | Unconjugated |
| Immunogen: | FAAP24 |
| Swiss port: | Q9BTP7 |
| Gene accession: | NP689479 |
| Celluar localization: | Nucleus |
FAAP24 (Fanconi anemia-associated protein of 24 kDa) plays a role in DNA repair by recruiting FA core complex to damage DNA. Regulate the effect of FANCD2 single base effect on DNA damage. When inhibited, it can cause chromosomal instability and hypersensitivity to DNA cross-linking agents. The FANCM/FAAP24 complex binds to DNA and preferentially binds to single-stranded DNA.
Diagnostic Development
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