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EV450 Anti-Mouse CD80 Antibody

  • Product Information
  • Description
Catalog: C-FC-1056A
Product Type: FCM Antibody
Size: 20 tests/50 tests/100 tests/500 tests
Reactivity: Mouse
Analysis mode: FCM
Host: Armenian Hamster
Isotype: Armenian Hamster IgG
Alternate names: T-lymphocyte activation antigen CD80,Cd80,Activation B7-1 antigen,B7
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: EV450
Buffer: PBS with 0.05% Proclin300, 1% BSA
Swiss port: Q00609
Clone NO.: 16-10A1
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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