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EV450 Anti-Mouse CD161/NK1.1 Antibody

  • Product Information
  • Description
Catalog: C-FC-1042A
Product Type: FCM Antibody
Size: 20 tests/50 tests/100 tests/500 tests
Reactivity: Mouse
Analysis mode: FCM
Host: Mouse
Isotype: Mouse IgG2a, κ
Alternate names: Killer cell lectin-like receptor subfamily B member 1C,Klrb1c,CD161 antigen-like family member C,Ly-55c,CD161/NK1.1,NKR-P1.9,NKR-P1C,NKR-P1 40,CD161c
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: EV450
Buffer: PBS with 0.05% Proclin300, 1% BSA
Swiss port: P27814
Clone NO.: PK136
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

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