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EV450 Anti-Human/Mouse/Rat CD47 Antibody

  • Product Information
  • Description
Catalog: C-FC-1036A
Product Type: FCM Antibody
Size: 20 tests/50 tests/100 tests/200 tests
Reactivity: Human, Mouse, Rat
Analysis mode: FCM
Host: Mouse
Isotype: Mouse IgG1, κ
Alternate names: Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: EV450
Buffer: PBS with 0.05% Proclin300, 1% BSA
Swiss port: Q08722,Q61735,P97829
Clone NO.: MIAP410
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

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