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EV450 Anti-Human CD69 Antibody

  • Product Information
  • Description
Catalog: C-FC-1034A
Product Type: FCM Antibody
Size: 20 tests/50 tests/100 tests/200 tests
Reactivity: Human
Analysis mode: FCM
Host: Mouse
Isotype: Mouse IgG1, κ
Alternate names: Early activation antigen CD69,Activation inducer molecule,AIM,EA1,MLR-3
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: EV450
Buffer: PBS with 0.05% Proclin300, 1% BSA
Swiss port: Q07108
Clone NO.: FN50
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

CD69 is a 27-33 kD type II transmembrane protein also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells.

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