ERBB4 polyclonal antibody

This gene (Verba erythroblastic leukemia viral oncogene homolog 4) belongs to the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-channel type I membrane protein with multiple cysteine-rich domains, transmembrane domains, tyrosine kinase domains, phosphoinositide-3 kinase binding sites and PDZ domain binding motifs. The protein binds to neuregulin and other factors and is activated, and induces various cellular responses including mitosis and differentiation.