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ER780 Anti-Mouse CD45 Antibody

  • Product Information
  • Description
Catalog: C-FC-0984A
Product Type: FCM Antibody
Size: 50 tests/100 tests/500 tests
Reactivity: Mouse
Analysis mode: FCM
Host: Rat
Isotype: Rat IgG2b, κ
Alternate names: Receptor-type tyrosine-protein phosphatase C,Ptprc,L-CA,Ly-5,T200,CD45
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: ER780
Buffer: PBS with 0.05% Proclin300, 1% BSA
Swiss port: P06800
Clone NO.: 30-F11
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

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