Catalog: | C-FC-0957A |
Product Type: | FCM Antibody |
Size: | 20 tests/50 tests/100 tests/200 tests |
Reactivity: | Human |
Analysis mode: | FCM |
Host: | Mouse |
Isotype: | Mouse IgG2a, κ |
Alternate names: | Monocyte differentiation antigen CD14,CD14,Myeloid cell-specific leucine-rich glycoprotein |
Form: | Liquid |
Shipping: | Biological ice pack at 4℃ |
Storage: | 2-8℃ |
Conjugation: | ER780 |
Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Swiss port: | P08571 |
Clone NO.: | M5E2 |
Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.
Copyright © 2024 Creative Biogene. All rights reserved.