Endocan human ELISA kit

Endocan is a soluble dermatan sulfate proteoglycan (DSPG) secreted by activated endothelial cells. It has the properties of binding to a variety of biologically active molecules related to cell signal transduction and adhesion, so it can regulate different cells in health and disease Types of proliferation, migration and adhesion. Endocan has been proved to be overexpressed in several human tumors such as lung cancer, uterine cancer, kidney cancer, liver cancer, glioblastoma, breast cancer, etc., and therefore is related to the pathogenesis of malignant tumors. Cancer angiogenesis is related. Studies have shown that high endoglucose serum levels are closely related to the presence of metastases and the limited survival of kidney cancer and lung cancer. The same relationship was also reported in a study of patients with hepatocellular carcinoma (HCC). It shows that elevated serum endoglin levels predict poor survival of patients. Many studies have emphasized the usefulness of Endcan as an early predictor of acute lung injury or respiratory failure in patients with severe trauma and septic shock. Higher serum endoglin levels It is related to the occurrence of postoperative pneumonia after heart surgery. Similarly, it was found that blood levels of endoglin were elevated in patients with sepsis and patients with bacterial infection with weakened immune function.