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ELAC2 polyclonal antibody

  • Product Information
  • Description
Catalog: C0091A
Product Type: Antibody
Reactivity: H,M,R
Analysis mode: WB,ELISA
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 0.7 mg/mL
Storage: -20℃
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Antigen affinity purification
Application: Cancer, Epigenetics and Nuclear Signaling
Conjugation: Unconjugated
Immunogen: ELAC2
Swiss port: Q9BQ52
Gene accession: BC001939
Celluar localization: Nucleus
Tissue specificity: Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes.

The synonym is HPC2 (heredity prostate cancer protein 2). The protein catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 and its nuclear partner forkhead box H1, and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer.

Verification Code

Diagnostic Development

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