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| Catalog: | C0811T |
| Product Type: | Test kit |
| Unit: | 96 tests |
| Regulatory status: | EU: CE |
| Incubation time: | 4 x 30min |
| Standard range: | 0 - 2000 pg/mL |
| Sample type: | Urine |
| Sample requirements: | 100 µL |
| Isotope/Substrate: | TMB 450 nm |
| Analysis mode: | ELISA |
| Application: | Metabolic Syndrome |
Dickkopf-3 (DKK3), a member of a family of Wnt-pathway modulators, was recently discovered as a stress-induced regulator of kidney fibrosis. DKK3 is originating from kidney tubular epithelial cells. Mechanistically, in pathological conditions DKK-3 deficiency causes a reduction in Wnt/ß-catenin signaling in tubular epithelial cells, accompanied by an enhanced inflammatory anti-fibrotic answer in the injured kidney tissue.
Diagnostic Development
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