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| Catalog: | C0357A |
| Product Type: | Antibody |
| Reactivity: | H,M |
| Analysis mode: | IHC,ELISA |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 0.5 mg/Ml |
| Storage: | -20℃ |
| Buffer: | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification method: | Antigen affinity purification |
| Application: | Cancer, Cardiovascular, Immunology, Microbiology |
| Conjugation: | Unconjugated |
| Immunogen: | CXCL12 |
| Swiss port: | P48061 |
| Gene accession: | NP000600 |
| Celluar localization: | Secreted |
| Tissue specificity: | Isoform Alpha and isoform Beta are widely expressed, with the highest levels detected in the liver, pancreas and spleen. Isoform Gamma is mainly expressed in the heart. |
Thymic lymphoma cell-stimulating factor (CXCL12) encodes a member of the alpha chemokine family derived from mesenchymal cells. The gene product and its receptor CXCR4 can activate lymphocytes and participate in the metastasis of breast cancer and other cancers. The mutation of this gene is related to the resistance to human immunodeficiency virus type 1 infection. This gene has been found to encode multiple transcriptional variants of different subtypes.
Diagnostic Development
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