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CXCL1 polyclonal antibody

  • Product Information
  • Description
Catalog: C0436A
Product Type: Antibody
Reactivity: H,M,R
Analysis mode: IHC,ELISA
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 1.02 mg/mL
Storage: -20℃
Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification method: Antigen affinity purification
Application: Cancer, Immunology
Conjugation: Unconjugated
Immunogen: CXCL1
Swiss port: P09341
Gene accession: NP001502
Celluar localization: Secreted

CXCL1 (C-X-C Motif Chemokine Ligand 1) is a protein coding gene. Diseases associated with CXCL1 include melanoma and bacterial meningitis. The related pathways include peptide ligand binding receptor and chemokine superfamily pathway: human/mouse ligand-receptor interaction. The GO annotations associated with this gene include receptor binding and chemokine activity. An important by-product of this gene is CXCL2. This antibacterial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the g protein-coupled receptor CXC receptor 2. This protein plays a role in inflammation and acts as a chemotactic agent for neutrophils. The abnormal expression of this protein is related to the growth and progression of certain tumors. A naturally occurring processed form of this protein increases chemotactic activity. The alternation of splicing leads to coding and non-coding mutations of the gene.

Verification Code

Diagnostic Development

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