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| Catalog: | C-FC-4649A |
| Product Type: | FCM Antibody |
| Size: | 5 µl/test |
| Reactivity: | Mouse |
| Positive FC: | rat splenocytes |
| Recommended dilution: | This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
| Analysis mode: | IF,FC |
| Host: | Rat |
| Isotype: | IgG2b |
| Alternate names: | Cd4, CD4 antigen, L3T4, Ly 4 |
| Storage: | 2-8°C |
| Purification method: | Affinity purification |
| Immunogen: | Mouse CTL clone V4 |
| Genn_ID: | 24932 |
| Gene symbol: | Cd4 |
| Buffer: | PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3. |
CD4 is a 55-kDa transmembrane glycoprotein expressed on T helper cells, majority of thymocytes, monocytes, macrophages, and dendritic cells (PMID: 9304802; 12213222). CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It plays an important role in T helper cell development and activation (PMID: 9539765; 3112582). CD4 serves as a receptor for the human immunodeficiency virus (HIV) (PMID: 9304802).
Core Diagnostic Capabilities
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