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| Catalog: | C-FC-4622A |
| Product Type: | FCM Antibody |
| Size: | 5 μl/test |
| Reactivity: | Human |
| Positive FC: | mouse splenocytes |
| Recommended dilution: | This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl per 10^6 cells in a 100 µl suspension or 5 µl per 100 µl of whole blood. |
| Analysis mode: | FC |
| Host: | Mouse |
| Isotype: | Mouse IgG1, kappa |
| Alternate names: | CD81, CD81 antigen, CD81 molecule, S5.7, TAPA1, Tetraspanin 28, Tspan 28, TSPAN28 |
| Storage: | 2-8°C |
| Purification method: | Protein G purification |
| Immunogen: | Human OCI-LY8 cell line |
| Genn_ID: | 12524 |
| Gene accession: | BC013807 |
| Gene symbol: | Cd86 |
| Buffer: | PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3. |
CD81 (also known as TAPA1or TSPAN28) is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Many of these members are expressed on leukocytes and have been implicated in signal transduction, cell-cell interactions, and cellular activation and development. CD81 is involved in signal transduction and cell adhesion in the immune system (PMID: 9597125). CD81 has also been identified as en essential receptor for HCV (hepatitis C virus) (PMID: 21428934).
Core Diagnostic Capabilities
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