Catalog: | C-FC-4616A |
Product Type: | FCM Antibody |
Size: | 5 µl/test |
Reactivity: | Human |
Positive FC: | mouse splenocytes |
Recommended dilution: | This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl per 10^6 cells in a 100 µl suspension or 5 µl per 100 µl of whole blood. |
Analysis mode: | FC |
Host: | Mouse |
Isotype: | Mouse IgG1, kappa |
Alternate names: | CD5, CD5 molecule, LEU1, Lymphocyte antigen T1/Leu 1, T1 |
Storage: | 2-8°C |
Purification method: | Affinity purification |
Immunogen: | N/A |
Genn_ID: | 15894 |
Gene accession: | BC008626 |
Gene symbol: | Icam1 |
Buffer: | PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3. |
CD5 is a type I transmembrane glycoprotein of the scavenger receptor cysteine-rich family (PMID: 12403363). CD5 is expressed on a majority of thymocytes, mature T cells, B cell subsets, and peripheral blood dendritic cells (PMID: 9858516; 6156984; 10379049; 1384337). CD5 may act as a receptor in regulating T-cell proliferation. It functions as a negative regulator of TCR signaling during thymocyte development (PMID: 7542801).
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