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CoraLite®647 Anti-Human CD5 (L17F12)

  • Product Information
  • Description
Catalog: C-FC-4615A
Product Type: FCM Antibody
Size: 5 μl/test
Reactivity: Human
Positive FC: Human peripheral blood lymphocytes
Recommended dilution: This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl(0.5µg) per 10^6 cells in a 100 µl suspension or 5 µl(0.5µg) per 100 µl of whole blood.
Analysis mode: FC
Host: Mouse
Isotype: Mouse IgG2a, kappa
Alternate names: CD5, CD5 molecule, LEU1, Lymphocyte antigen T1/Leu 1, T1
Storage: 2-8°C
Purification method: Protein A purification
Immunogen: Human T-cell acute lymphoblastic leukemia (T-ALL) cells
Genn_ID: 921
Gene accession: BC027901
Gene symbol: CD5
Buffer: PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3.

CD5 is a type I transmembrane glycoprotein of the scavenger receptor cysteine-rich family (PMID: 12403363). CD5 is expressed on a majority of thymocytes, mature T cells, B cell subsets, and peripheral blood dendritic cells (PMID: 9858516; 6156984; 10379049; 1384337). CD5 may act as a receptor in regulating T-cell proliferation. It functions as a negative regulator of TCR signaling during thymocyte development (PMID: 7542801).

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