| Catalog: | C-FC-4615A |
| Product Type: | FCM Antibody |
| Size: | 5 μl/test |
| Reactivity: | Human |
| Positive FC: | Human peripheral blood lymphocytes |
| Recommended dilution: | This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl(0.5µg) per 10^6 cells in a 100 µl suspension or 5 µl(0.5µg) per 100 µl of whole blood. |
| Analysis mode: | FC |
| Host: | Mouse |
| Isotype: | Mouse IgG2a, kappa |
| Alternate names: | CD5, CD5 molecule, LEU1, Lymphocyte antigen T1/Leu 1, T1 |
| Storage: | 2-8°C |
| Purification method: | Protein A purification |
| Immunogen: | Human T-cell acute lymphoblastic leukemia (T-ALL) cells |
| Genn_ID: | 921 |
| Gene accession: | BC027901 |
| Gene symbol: | CD5 |
| Buffer: | PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3. |
CD5 is a type I transmembrane glycoprotein of the scavenger receptor cysteine-rich family (PMID: 12403363). CD5 is expressed on a majority of thymocytes, mature T cells, B cell subsets, and peripheral blood dendritic cells (PMID: 9858516; 6156984; 10379049; 1384337). CD5 may act as a receptor in regulating T-cell proliferation. It functions as a negative regulator of TCR signaling during thymocyte development (PMID: 7542801).
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