Catalog: | C-FC-4612A |
Product Type: | FCM Antibody |
Size: | 5 µl/test |
Reactivity: | Human |
Positive FC: | SJL mouse splenocytes |
Recommended dilution: | This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl per 10^6 cells in a 100 µl suspension or 5 µl per 100 µl of whole blood. |
Analysis mode: | FC |
Host: | Mouse |
Isotype: | Mouse IgG1, kappa |
Alternate names: | B220, CD45, CD45R, GP180, L CA, LCA, Leukocyte common antigen, LY5, PTPRC, RPTPC, T200 |
Storage: | 2-8°C |
Purification method: | Affinity purification |
Immunogen: | Human PBMC |
Genn_ID: | 19264 |
Gene accession: | BC028512 |
Gene symbol: | Ptprc |
Buffer: | PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3. |
CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097).
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