Catalog: | C-FC-4601A |
Product Type: | FCM Antibody |
Size: | 5 μl/test |
Reactivity: | Human |
Positive FC: | Human peripheral blood lymphocytes |
Recommended dilution: | This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl(0.25µg) per 10^6 cells in a 100 µl suspension or 5 µl(0.25µg) per 100 µl of whole blood. |
Analysis mode: | FC |
Host: | Mouse |
Isotype: | Mouse IgG1, kappa |
Alternate names: | CD29, FNRB, GPIIA, Integrin beta 1, ITGB1, MDF2, MSK12, VLA 4 subunit beta, VLA BETA, VLAB |
Storage: | 2-8°C |
Purification method: | Protein G purification |
Immunogen: | N/A |
Genn_ID: | 916 |
Gene accession: | BC049847 |
Gene symbol: | CD3E |
Buffer: | PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3. |
Integrin beta-1 (ITGB1), also named as CD29, is a 130 kDa single chain type I glycoprotein that is expressed in a heterodimeric complex with one of six distinct α subunits, comprising the very late activation antigen (VLA) subfamily of adhesion receptors. It is one of the essential surface molecules expressed on human MSC from bone marrow and other sources. The β1 subunit is also broadly expressed on lymphocytes and monocytes, weakly expressed on granulocytes, and not expressed on erythrocytes. These receptors are involved in a variety of cell-cell and cell-matrix interactions.
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