USA: 
Europe: 
Email: 
Consultation
| Catalog: | C-FC-4568A |
| Product Type: | FCM Antibody |
| Size: | 5 µl/test |
| Reactivity: | Mouse |
| Positive FC: | mouse bone marrow cells |
| Recommended dilution: | This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl per 10^6 cells in a 100 µl suspension or 5 µl per 100 µl of whole blood. |
| Analysis mode: | IF,FC |
| Host: | Armenian Hamster |
| Isotype: | IgG |
| Alternate names: | T cell receptor beta chain, Tcrb, Tib |
| Storage: | 2-8°C |
| Purification method: | Affinity purification |
| Immunogen: | Affinity purified TCR from mouse DO-11.10 cells |
| Genn_ID: | 104231 |
| Gene symbol: | Ly76 |
| Buffer: | PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3. |
T-cell receptor (TCR) consists of heterodimeric glycoproteins (TCR alpha/beta or gamma/delta) that demonstrate homology with immunoglobulins (PMID: 2144901). TCR beta is a member of the immunoglobulin superfamily and is expressed on alpha/beta TCR-bearing T cells and thymocytes. The TCR heterodimers are noncovalently associated with CD3. The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta (PMID: 1826255). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).
Core Diagnostic Capabilities
Follow Us -
Copyright © 2025 Creative Biogene. All rights reserved.
