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| Catalog: | C0486A |
| Product Type: | Antibody |
| Analysis mode: | WB, IHC, ELISA |
| Species specificity: | Human, mouse, rat |
| Host: | Mouse |
| Clonality: | Monoclonal |
| Isotype: | IgG1 |
| Concentration: | 1000 μg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.1% sodium azide and 50% glycerol pH 7.3 |
| Purification method: | Protein G purification |
| Conjugation: | Unconjugated |
| Immunogen: | CDK4 |
| Genn_ID: | 1019 |
| Gene accession: | BC010153 |
Cyclin-dependent kinase-4 (CDK4) is a protein-serine kinase involved in the cell cycle. The transition of G1- to s phase in the cell cycle is essential, and its expression is mainly controlled at the transcriptional level. The CCND1-CDK4 axis is essential not only in glial tumor cells, but also in stromal-derived cells that are essential for maintaining tumor growth in the surrounding tumor microenvironment.
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