CD63 monoclonal antibody

CD63 plays an important role in the body's immune and physiological functions. It mediates signal transduction events that play a role in regulating cell development, activation and movement. CD63 is expressed on activated platelets, so it may serve as a platelet activation marker. CD63 is a lysosomal membrane glycoprotein that easily locates in the plasma membrane after platelet activation. CD63 tetraspanin is highly expressed in the early stage of melanoma and decreased in the advanced disease, suggesting that it may be an inhibitor of tumor progression. The lack of this protein is related to Hermansky-Pudlak syndrome.