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| Catalog: | C0037A |
| Product Type: | Antibody |
| Reactivity: | H,M,R |
| Analysis mode: | IHC |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/mL |
| Storage: | -20°C |
| Buffer: | PBS with 0.05% Proclin300 and 50% glycerol, pH7.3 |
| Purification method: | Antigen affinity purification |
| Application: | Immunology |
| Conjugation: | Unconjugated |
| Immunogen: | CD109 |
| Swiss port: | Q6YHK3 |
| Genn_ID: | 135228 |
| Celluar localization: | Cell membrane, Membrane |
CD109, also known as CPAMD7, is a member of the alpha2-macroglobulin/complement superfamily. CD109 binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes. Up regulation of CD109 expression has been observed in several different types of tumor. Multiple transcript variants encoding different isoforms have been found for CD109.
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