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CCDC112 polyclonal antibody

  • Product Information
  • Description
Catalog: C0251A
Product Type: Antibody
Reactivity: H,M
Analysis mode: IHC,ELISA
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 0.5 mg/mL
Storage: -20℃
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: Cell Biology
Conjugation: Unconjugated
Immunogen: CCDC112
Swiss port: Q8NEF3
Gene accession: BC031242

CCDC112, also known as MBC1 (bladder cancer 1 mutation), is a 446 amino acid protein. The gene encoding CCDC112 is located on chromosome 5. Due to different splicing events, CCDC112 exists as two isoforms. Chromosome 5 accounts for about 6% of human genomic DNA, contains 181 million base pairs, and encodes about 1,000 genes. The ERCC8 gene is associated with Cockayne syndrome, and the APC tumor suppressor gene is associated with familial adenomatous polyposis. Treacher Collins syndrome is also related to chromosome 5 and is caused by the insertion or deletion of the TCOF1 gene. The deletion of the p-arm of chromosome 5 causes Cri du chat syndrome. Deletion of 5q or 5 chromosome is common in treatment-related acute myelogenous leukemia and myelodysplastic syndromes.

Verification Code

Diagnostic Development

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