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C8orf4 polyclonal antibody

  • Product Information
  • Description
Catalog: C0422A
Product Type: Antibody
Reactivity: H,M
Analysis mode: IHC,ELISA
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 1.26 mg/Ml
Storage: -20℃
Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification method: Antigen affinity purification
Application: Cancer, Epigenetics and Nuclear Signaling, Signal transduction, Stem cells
Conjugation: Unconjugated
Immunogen: C8orf4
Swiss port: Q9NR00
Gene accession: BC020623

The gene encodes a small, monomeric, mainly non-structural protein that acts as a positive regulator of the Wnt/ -catenin signaling pathway. The protein interacts with a transcription repressor mediated by catenin in nuclear spots. It is thought to competitively block the interaction between inhibitors and catenin, leading to the up-regulation of target genes for catenin. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. The expression of this gene may play a role in the proliferation of a variety of cancers including thyroid cancer, breast cancer and hematological malignancies.

Verification Code

Diagnostic Development

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