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| Catalog: | C0008A |
| Product Type: | Antibody |
| Reactivity: | M,R |
| Analysis mode: | WB,IHC |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.05% Proclin300 and 50% glycerol, pH7.4 |
| Purification method: | Antigen affinity purification |
| Application: | Cancer, Cardiovascular, Metabolism, Immunology, Neuroscience |
| Conjugation: | Unconjugated |
| Immunogen: | BSG |
| Swiss port: | P26453 |
| Genn_ID: | 25246 |
| Celluar localization: | Cell membrane |
| Tissue specificity: | Isoform 1 is specifically expressed in retina. Isoform 3 is widely expressed, including adult organs, embryos and EC cells. |
BSG, also named as CD147, plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. CD147 is a receptor of CypA, inducing matrix metalloproteinase expression and mediating the degradation of the extracellular matrix, plays an important role in tumorigenesis and invasion in colorectal cancer. It has been considered as an objective and effective marker to predict invasion and prognosis in various cancers.
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