Catalog: | C0786A |
Product Type: | Antibody |
Analysis mode: | WB, ELISA |
Species specificity: | Human |
Host: | Rabbit |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 730 μg/mL |
Storage: | -20℃ |
Buffer: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 |
Purification method: | Antigen affinity purification |
Conjugation: | Unconjugated |
Immunogen: | BRIP1 |
Genn_ID: | 83990 |
Gene accession: | NM032043 |
BRIP1, also known as BACH1 and FANCJ. It is a DNA-dependent atp enzyme and 5'to 3'DNA helicase to maintain chromosome stability. It participates in the repair of DNA double-strand breaks through homologous recombination, and its repair method depends on its combination with BRCA1. The defect of BRIP1 is a cause of breast cancer susceptibility (BC). BRIP1 deficiency is the cause of Fanconi anemia complementation group J (FANCJ). This antibody is specific for BRIP1.
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